Abstract:
The present study provides the pharmacological evaluation of stem bark extract of Jatropha curcas L. for anti-diarrhoeal activity in rats. We made an attempt to study the effect of stem bark extract of Jatropha curcas L. on diarrhoeal disease. The different activities studied were castor oil-induced diarrhoea, magnesium sulphate induced diarrhoea and charcoal meal transit test. The result of the study reflected that methanol extract of the stem bark (100, 300 mg/kg) decreased total no. of faeces, wet faeces and distance travelled by charcoal plug and showed the antidiarrhoeal activity. Jatropha curcas L. extract demonstrates the anti-diarrhoeal activity in rats.

Keywords: Castor Oil-induced Diarrhoea, Charcoal Meal Transit Test, Diarrhoeal, Jatropha curcas, Magnesium Sulphate Induced Diarrhea.