Abstract:
“Hand hygiene” is the primary goal in making a polyherbal hand sanitizer. It is an essential idea for the reduction, management, and prevention of any acquired infection. Generally speaking, hand sanitizers can break the chain of microbes and other bacteria that travel from our hands to other areas of our bodies. Maintaining good hand hygiene is crucial and one of the most important things to do when preparing food in homes, restaurants, and other day care facilities. Using hand sanitizer can prevent side effects such as dermatitis, itching, and irritation. Using five herbal extracts, distilled water, ethanol, methyl paraben, glycerol, and isopropyl alcohol, we made a polyherbal sanitizer. The compounds’ antibacterial qualities were taken into account prior to selection. It was discovered that the sanitizer’s pH ranged from 6.11 to 6.85. It was discovered that the sanitizer’s viscosity ranged from 380 to 800 cps. The range of 6.40 to 7.80 was determined to have high spreadability. For Mentha, the drug content in formulations was 88.6% in F1, 90.2 % in F2, and 92.8 % in F3. Similarly, for Tulsi, the drug content in formulations was 86.4% in F1, 93.1 % in F2, and 95.6% in F3. The results of the in-vitro drug release investigation showed that F1 was 65.9%, F2 was 70.5%, and F3 was 73.9%. The formulation F3 is the best, according to all of these investigations, because it has better drug content, pH, viscosity, spread ability, and in-vitro drug release trials.

Keywords: Herbal Extracts, Hand Hygiene, Anti-microbial Agents, Dispersion.